Research Associate, Viral Vector Process Development

Job Description

Bristol-Myers Squibb(BMS) is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health.  We value our passion for patients, ​quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

The Research Associate will join our viral vector process development group supporting process development, production and characterization of AAV vectors, which are key intermediates in the generation of multiple T-cell derived drug products.  The candidate will support AAV programs and advance our capabilities in vector production.

Responsibilities:

  • Hands-on experimental work in the development and optimization of upstream (cell culture and transfection conditions) and downstream (clarification, tangential flow filtration, chromatography) unit operations for viral vector production
  • Support the process development program for AAV vector manufacturing platforms
  • Contribute to the planning and design of experiments, execution and independent analysis of data
  • Problem-solving and troubleshooting exist process designs, and technologies, using scale-down models
  • Maintain proper documentation of experimental results.
  • Support process transfer, development, and manufacturing at external CMOs.

Basic Qualifications:

  • B.S. in Bioengineering, Chemical Engineering, Virology, Biology, Biochemistry, or related discipline
  • 0-2 years of industry experience in process development
  • Independently motivated with the ability to work in teams
  • Ability to communicate clearly and concisely through oral presentation and technical writing

Preferred  Qualifications:

  • Demonstrated ability to read and understand scientific literature
  • Experience in mammalian cell culture, transfection, harvest, and purification of biological products
  • Familiarity with basic analytical assay formats (e.g. ELISA, PCR, flow cytometry etc.) and ability to operate associated analytical equipment