Research Associate, Product Sciences

Job Description


The Cell Therapy Product Sciences department is seeking a Research Associate to support the development of early stage CAR T and engineered TCR cell products. The Product Sciences Team is responsible for developing and executing mechanism of action and characterization studies to support the development of gene-engineered T cell therapies. The primary focus of the Product Sciences Research Associate role will be to build CAR T cell product and process understanding in support of pipeline projects. Successful candidates will have a strong foundation in immunology and/or human T cell biology and experience with implementation and optimization of a broad range of in vitro cell-based and molecular assays.  This role is highly collaborative and will require an individual that is highly motivated to learn, develop, and apply new techniques and technologies to understanding CAR T and engineered TCR cell function.

REQUIRED COMPETENCIES:  Knowledge, Skills, and Abilities:


BS in Biology, Cell Biology, Biochemistry, Immunology, or relevant discipline


Qualifications and Education Requirements

  • B.S. degree in immunology or related field with 0-2 years relevant experience.
  • Experienced with cell culture and primary human cells
  • Experience with multi-parameter flow cytometry
  • Ability to work in a high paced team environment, meet deadlines, & prioritize work on multiple projects.
  • Excellent interpersonal, written and verbal communication skills and attention to detail
  • Outstanding written and oral communication skills
  • Work effectively in a collaborative team setting
  • Ability to work in a rapidly changing environment with frequent changes in priorities
  • Experience with MS Office suite of software

Preferred Qualifications

  • Knowledge of human T cell biology and analytical tools for interrogating T cell phenotype and function.
  • Experience with in vitro T cell functional assays
  • Experience with cellular therapy development
  • Experience with gene expression methods and technologies
  • Multi-dimensional flow cytometry analysis


  • Participate in cross-functional teams to support the development of gene-engineered T cell therapeutic platforms.
  • Identification and prioritization of novel analytical approaches for interrogating gene-engineered T cell function.
  • Design and deploy in-depth characterization of gene-engineered T cells using flow cytometry, genome-wide expression analysis, metabolic profiling, and additional cutting-edge analytical techniques.
  • Perform instrument and method troubleshooting
  • Ability to execute experiments with limited guidance and supervision
  • Maintain meticulous laboratory notebooks
  • Help author, review and approve technical documents, including methods, protocols, reports, and SOPs
  • Learn and apply ICH/FDA/EMEA guidance and current thinking.
  • Facilitate smooth operation of the laboratory, including ordering, sample management, etc.


  • Office and laboratory environments with a mix of natural and LED lighting with low level of background noise.  Required computer and conferencing hardware are provided.  40% seated at a desk with ergonomic and sit/stand desks and 60% time in laboratory or meetings.
  • Local, national, and international travel up to 5%
  • This job description is intended to describe the general nature and level of work being performed by the person assigned to this position. The primary duties and responsibilities are intended to describe those functions that are essential to the performance of this job.
  • This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. There are other duties and responsibilities that are considered incidental or secondary to the overall purpose of this job. Employees holding this position will be required to perform any other job-related duties as requested by management.