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Sr Director, Neuroscience

Req #: 1800512
Location: San Diego, CA US
Job Category: Research and Early Development
Work Location: 3033 Science Park Road Suite 300 RCPTSD 92121
Organization: Receptos, Inc.
Schedule: 40
Employee Status: Full time
Job Type: Regular
Job Level:
Other Locations:US- CA- San Diego- Science Park


Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health.  We value our passion for patients, ​quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Receptos is seeking a seasoned drug developer with specific and deep scientific expertise in CNS indications. This Sr. Director of Neurology who will be responsible for guiding the strategy within the CNS area and leading a group of in vitro and in vivo scientists to discover and develop drug candidates within neurology.  In addition to building a robust in-house small molecule drug discovery pipeline, the Sr. Director of Neurology will guide the diligence of potential in-licensing of preclinical and clinical stage assets.  A Sr. Director will have excellent communication, interpersonal and management experience and skills to collaborate and direct the research efforts. He or she will work cross-functionally to set project priorities, develop and mentor staff, as well as manage budgets and resources. The successful candidate will interface with the Research, Clinical, Commercial, and Translational Teams.

This position is located at our San Diego (Science Park) facility.

Major Responsibilities:

  • Lead and direct the neurobiology of all in-house drug discovery programs.
  • Interact closely and build consensus with the Chemistry and Preclinical Sciences teams.
  • Build an in-house discovery pipeline by leading a cross-functional team in the identification of compelling new small molecule drug targets in CNS diseases and initiating new drug discovery programs.
  • Develop staffing plans to support discovery pipeline expansion.
  • Collaborate with Preclinical Sciences in the development of animal models with neurology, planning IND-enabling studies and contributing to the preparation of Regulatory documents
  • Manage the Neurobiology budget.
  • Establish and manage both academic and commercial external alliances.
  • Responsible for Scientific Advisory Board meetings.
  • Responsibility for CNS-focused manuscripts and conference presentations.
  • An integral member of a cross-functional in-licensing due diligence team whose responsibilities include identifying and building a robust pipeline of assets, spanning preclinical to clinical programs.
  • Interface with the Translational Medicine team; provide input and guidance on translational research activities for all clinical stage programs.
  • Interface with Executive Team and Board of Directors.
  • Other responsibilities as assigned.

Knowledge and Skill Requirements:

  • PhD in Biology/Neurology with industry experience and in-depth knowledge of Neurology.
  • Proven success of pre-clinical drug development within the CNS indications leading to drugs in the clinic.
  • Prior experience as Head of Neurology within the biotechnology or pharmaceutical industry.
  • Proven ability to guide strategy and deliver drug products within the CNS space.
  • Proven ability to champion and advance innovative concepts and build pipelines.
  • Demonstrated strategic, operational, organizational and intellectual leadership.
  • Experience in strategic planning, project leadership, laboratory and budget management.
  • Effective communicator and ability to influence and develop a high performance team.
  • Expertise in small molecule pharmacokinetics/pharmacodynamics, biochemistry, and pharmacology with broad understanding of the physiological principles of health and disease.
  • Solid grasp of chemistry, and mechanisms of drug metabolism and molecular toxicology.


Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.
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Celgene is a global biopharmaceutical company committed to improving the lives of patients worldwide. At Celgene, we seek to deliver truly innovative and life-changing treatments for our patients.

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