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Senior Scientist, Translational Medicine

Req #: 1700875
Location: Summit, NJ US
Job Category: Research and Early Development
Work Location: 556 Morris Avenue CELSUMWEST 07901
Organization: Celgene Corporation
Schedule: 0
Employee Status: Full time
Job Type: Regular
Job Level:
Other Locations:US- NJ- Summit West


Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health.  We value our passion for patients, ​quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Senior Scientist, Translational Medicine


Reporting to Director Translational Development, the senior scientist will be part of the late stage translational group based in Summit NJ and will be a key contributor as a lead translational scientist. This exciting opportunity will position the candidate within a matrixed team in the B-cell malignancy group with a focus on multiple myeloma. Key responsibilities of this role are to act as the translational representative in Project teams for myeloma program with sharing of ideas across lymphoma as well as myeloid disease areas and assume primary responsibilities for supporting projects in key strategic areas. The overarching goals of these efforts will be to support the hematological oncology portfolio by contributing to decision-enabling biological understanding of tumoral and immune context of hematalogical disease.  


  • Manage existing key translational collaborations and help set up new collaborations  
  • Contributes to the review of external preclinical proposals, key investigator initiated studies as well as trials proposals that include correlatives
  • Contribute to the development of translational program budgets for assigned external collaborative projects  
  • Creates Schedule of  work and interfaces with CRO for execution of services
  • Oversee validation of biomarker assays for robustness and inclusion in regulatory filings
  • Assists in the development of disease specific strategy
  • Communicates regularly and prepares and makes presentations within the department and externally as required
  • Represents Translational Development in Project team/Franchise team, other cross-functional teams as needed

Requirements & Education:

PhD  in life sciences or medical sciences, and a minimum of 5 years of directly relevant biotechnology or pharmaceutical industry experience.  Candidate must be detail-oriented with excellent record keeping and organizational skills. Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast-paced dynamic environment.  

Technical Skills/Qualifications:

  • Strong background in hematology/oncology biology, especially Multiple Myeloma
  • Broad understanding of drug discovery & development especially late stage development and approval process and life cycle management.
  • Experience in clinical development process in an industry setting including in clinical assay development; clinical biomarker discovery is essential 
  • Knowledge of GLP, assay validation methodologies, and regulations that apply to clinical laboratory studies that support regulatory submissions is required. 
  • Authoring of biomarker portion of clinical protocols, drug study reports, regulatory submissions 
  • Analysis of biomarker data in preclinical and clinical setting. Detail-oriented with the ability to synthesize complex scientific and business problems into strategy and tactics
  • Extensive working knowledge of biomedical research methodologies and current state-of-the art genetic analysis technologies (familiarity with single cell analytics platforms such as CyTOF, Cite-Seq, and 10X Genomics Chromium considered a plus.)
  • Understanding of established cell line culture techniques as well as primary culture establishment and manipulation a requirement
  • Working knowledge and hands-on experience with FACS analysis. 
  • Immunophenotyping and understanding of immune-oncology would be considered a strong plus.
  • Basic understanding of technical aspects of companion diagnostics development; partnerships, due diligence experience, project experience (IDE development; Diagnostic protocol etc.)   
  • Proven scientific/leadership expertise (working in matrixed teams, managing multiple people/projects)    
  • Proven publication record   
  • Strong verbal and written communication skills 



Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.
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