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Senior Director, Chemistry - San Diego, CA

Req #: 17001209
Location: San Diego, CA US
Job Category: Research and Early Development
Work Location: San Diego, CAD3 10300 Campus Point Drive Suite 100 San Diego 92121
Organization: Signal
Schedule: Full-time
Shift: Day Job
Employee Status: Regular
Job Type: Standard
Job Level: Director
Travel: No


Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health.  We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.


The candidate will lead multiple internal and external research programs in the Chemistry Department at Celgene’s San Diego research facility.  The candidate will have outstanding leadership and team management skills, with a demonstrated ability to coordinate and direct the efforts of multiple staff incorporating various scientific skills and disciplines. This position will report to the VP of Chemistry and manage a large department based in San Diego.  The successful candidate will work directly with the Project Teams and Early Development Teams, therapeutic area leadership, other research disciplines, and CROs. 


•Oversee an innovative chemistry team that is a reliable source of high-quality development candidates.

•Manage all chemistry activities, personnel, and operations in San Diego.

•Accountable for project strategies, timelines, and deliverables.

•Interact effectively with partners in computational chemistry, biochemistry, pharmacology, DMPK, toxicology, and early development.

•Supervise and direct the efforts of all chemistry staff, providing guidance, instruction, and coaching. 

•Represent chemistry across and beyond Discovery.

•Build a dynamic scientific and professional culture focused on productivity and innovation that reflects Celgene values.

•Manage to budget.


Requirements & Education:

PhD in organic or medicinal chemistry with >15 years of relevant biotechnology or pharmaceutical industry experience.  Candidate must have demonstrated the delivery of multiple compounds into clinical development. Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast-paced dynamic environment.

•PhD in chemistry with >15 years of relevant drug discovery experience.
•Widely recognized as an intellectual leader in medicinal chemistry and drug discovery with an extensive record of patents and publications.
•Demonstrated track record of delivering multiple candidates into development.
•Significant project leadership experience.
•Demonstrated ability to implement project and chemistry strategies.
•In-depth knowledge of multiple therapeutic areas.
•Experience in both Discovery and Early Development stages of drug discovery.
•Extensive working knowledge of modern medicinal chemistry and drug discovery techniques (FBDD, SBDD, multi-attribute analysis, flexible resourcing models, alternative delivery systems, etc.).
•Experience with the concepts and methods of parallel synthesis.
•Experience managing scientific collaborations and contracted research.
•Effective team building and teamwork skills.


•Expert in medicinal chemistry – both drug design and organic synthesis.
•Able to integrate heterogeneous and ambiguous data streams and formulate coherent paths forward.
•Excellent written and oral communication skills.
•Facilitates the growth of less experienced scientists. 
•Effective spokesperson for medicinal chemistry across the Celgene organization.
•Broad understanding of drug discovery & development and the R&D process.
•Familiar with industry trends and competitors position.

Other Attributes:
•Develop new, innovative approaches to project leadership and management.
•Allocate resources that affect the department.
•Collaborate with VP in developing goals for chemistry in San Diego.
•Build constructive relationships across the Celgene organization to achieve the goals of Chemistry and the business.
•Represent Celgene Research to the external scientific community through conferences, lectures, and publications.
•Optional experience in non-small molecule (biologics) drug discovery.

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.

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About Celgene

Celgene is a global biopharmaceutical company committed to improving the lives of patients worldwide. At Celgene, we seek to deliver truly innovative and life-changing treatments for our patients.

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